Breaking news on transplants-organ_donations
After Stem Cell Transplant For Multiple Myeloma Patients, Lenalidomide Prolongs Disease Control published
Wed, 16 May 2012 09:00:00 PDT
Multiple myeloma patients are better equipped to halt progression of this blood cancer if treated with lenalidomide, or Revlimid®, following a stem cell transplant, according to a study co-authored by a physician with the Oregon Health & Science University Knight Cancer Institute...
Controlling Inflammation: Novel Drug Candidates Offer New Route published
Wed, 16 May 2012 00:00:00 PDT
Pursuing a relatively untapped route for regulating the immune system, an international team of researchers has designed and conducted initial tests on molecules that have the potential to treat diseases involving inflammation, such as asthma, rheumatoid arthritis, stroke and sepsis...
New Maintenance Therapy Benefits Patients With Multiple Myeloma published
Mon, 14 May 2012 01:00:00 PDT
Multiple myeloma is a form of cancer where the plasma cells in the bone marrow grow out of control, causing damage to bones as well as predisposing patients to anemia, infection and kidney failure. A medical procedure called autologous hematopoietic stem cell transplantation, commonly known as a stem cell transplant, is frequently an important treatment option for many patients...
Kidney Donation Hindered By Obesity published
Sat, 12 May 2012 00:00:00 PDT
Researchers at the Hofstra North Shore-LIJ School of Medicine and Feinstein Institute for Medical Research conducted a retrospective analysis which found that morbid obesity impedes kidney donation...
Problems In Transport Of Donated Human Retina Led Researchers To Discover New Treatment Path For Eye Disease published
Tue, 08 May 2012 00:00:00 PDT
Sloppy shipping of a donated human retina to an Indiana University researcher studying a leading cause of vision loss has inadvertently helped uncover a previously undetected mechanism causing the disease. The discovery has led researchers to urge review of how millions of dollars are spent investigating the cause of a type of age-related macular degeneration called choroidal neovascularization...
Living Kidney Donors Benefit From New Imaging Protocols published
Tue, 01 May 2012 00:00:00 PDT
A new study from UCLA shows how magnetic resonance angiography (MRA) and computed tomography angiography (CTA) are equivalent in delineating anatomy in living renal donors. In a study that examined 30 patients and 60 kidneys, both modalities were "excellent" in detecting the number of renal arteries and veins. Dr...
Transplantation Of Fetal Membrane To Prevent Blindness published
Mon, 30 Apr 2012 01:00:00 PDT
Transplanting tissue from newborn fetal membranes prevents blindness in patients with a devastating disease called Stevens-Johnson syndrome, a Loyola University Medical Center study has found. The study by senior author Charles Bouchard, MD, and colleagues is published online ahead of print in the journal Cornea...
No Increase In Mortality Rates For Liver Transplants Performed At Night And Weekends published
Mon, 30 Apr 2012 00:00:00 PDT
A new study, funded in part by a grant from the National Institutes of Health (NIH), shows that liver transplants performed at night or on weekends do not adversely affect patient or graft survival...
Transplant Recipient Donates Kidney After Disease Threatens The Organ; Re-Implantation Reverses Damage And Allows Another Patient To Thrive published
Fri, 27 Apr 2012 01:00:00 PDT
For the first time, a kidney that had been donated to a patient in need was removed and implanted into a new patient, the third individual to have the organ, after it failed in the first transplant recipient...
Animal Model For Xenotransplantation As A Therapy For Type 1 Diabetes published
Wed, 25 Apr 2012 01:00:00 PDT
Type1 diabetes is caused by autoimmune destruction of the insulin-producing beta cells. Over 250,000 patients suffer from type 1 diabetes in Germany who are treated with daily insulin injections to maintain glucose metabolism. Replacement of the destroyed beta cells by transplantation of either a complete pancreas organ or isolated human beta cells is the only effective way to cure the disease...
Bioengineered Follicles Grow Hair On Bald Mice published
Sat, 21 Apr 2012 00:00:00 PDT
In a proof of concept study for bioengineered organ replacement, researchers in Japan made hair follicles derived from adult stem cells interact with surrounding tissue and show normal hair cycles, when transplanted into the skin of bald mice...
Diabetic Amputations Reduced By Autologous Bone Marrow-Derived Mononuclear Cell Transplants published
Fri, 20 Apr 2012 01:00:00 PDT
Autologous (self-donated) mononuclear cells derived from bone marrow (BMMNCs) have been found to significantly induce vascular growth when transplanted into patients with diabetes who are suffering from critical limb ischemia caused by peripheral artery disease (PAD), a complication of diabetes...
Combined, Complimentary Therapies Maximize Neural Stem Cell Transplants For Spinal Cord Injury published
Thu, 19 Apr 2012 01:00:00 PDT
Combined, complimentary therapies have the ability to maximize the benefits of neural stem cell (NSC) transplantation for spinal cord repair in rat models, according to a study carried out by a team of Korean researchers who published in a recent issue of Cell Transplantation (20:9), now freely available on-line...
Balancing The Immune System: Discovery Could Aid In The Development Drugs For Organ Transplant, Autoimmune Disorders And Cancer published
Mon, 16 Apr 2012 00:00:00 PDT
Loyola researchers are reporting surprising findings about a molecule that helps ramp up the immune system in some cases and suppress it in others. The finding eventually could lead to new drugs to regulate the immune system by, for example, revving it up to attack tumor cells or tamping it down to prevent the rejection of transplanted organs...
Corneal Thickness Linked To Early Stage Fuchs' Endothelial Corneal Dystrophy published
Wed, 11 Apr 2012 02:00:00 PDT
A national consortium of researchers has published new findings that could change the standard of practice for those treating Fuchs' Endothelial Corneal Dystrophy (FECD), a disease characterized by cornea swelling that can eventually lead to the need for corneal transplantation...
Higher Glucose Levels May Benefit Heart Failure Patients With Diabetes published
Wed, 11 Apr 2012 01:00:00 PDT
Lowering glucose levels for people with diabetes is normally critical to improving health outcomes. But for those with heart failure, that might not always be the case, say UCLA researchers. A new study found that for advanced heart failure patients with diabetes, having higher blood glucose levels may actually help improve survival rates...
Rapamycin Can Cause Diabetic-Like State published
Tue, 10 Apr 2012 11:00:00 PDT
A study published in Cell Metabolism reports that scientists at the Dana-Farber Cancer Institute have discovered why some patients who receive rapamycin, an immuno-suppressant that also has anti-cancer activity, and may even slow ageing, have developed symptoms similar to diabetes...
From Cancer Drug To Diabetes published
Thu, 05 Apr 2012 01:00:00 PDT
The drug known as rapamycin is widely used by cancer and transplant patients, and there are hints that it might even help us put off old age and live longer. But, it also comes with a downside: rapamycin leads to diabetes in as many as 15 percent of the people who take it. Now, researchers reporting in the April Cell Metabolism, a Cell Press publication, have figured out why that is...
Scientists Find Promising Vaccine Targets On Hepatitis C Virus published
Thu, 05 Apr 2012 01:00:00 PDT
A team led by scientists at The Scripps Research Institute has found antibodies that can prevent infection from widely differing strains of hepatitis C virus (HCV) in cell culture and animal models. HCV's very high rate of mutation normally helps it to evade its host's immune system. The newly discovered antibodies, however, attach to sites on the viral envelope that seldom mutate...
News From The Annals Of Internal Medicine: April 3, 2012 published
Wed, 04 Apr 2012 00:00:00 PDT
1. Mammography Screening Leads to Overdiagnosis of Breast Cancer Women undergo mammography screening to detect cancer in its early stages. Theoretically, early detection saves lives. However, newer research is questioning whether finding cancer early is better. Researchers in Norway sought to determine the percentage of overdiagnosis of breast cancer attributable to mammography screening...
Effective Prevention And Treatment Of Graft-Versus-Host Disease May Be Possible Following New Discovery published
Tue, 03 Apr 2012 00:00:00 PDT
A new discovery in mice may lead to new treatments that could make bone marrow transplants more likely to succeed and to be significantly less dangerous...
Organ Transplant Fluid May Be Contaminated, UK published
Fri, 30 Mar 2012 02:00:00 PDT
The Department of Health in England says that Viaspan, a manufactured fluid used to preserve some donor organs when they are moved, could have been contaminated with the bacterium, Bacillus cereus since last July. Viaspan is a sterile, cold solution that is widely used for storing and transporting abdominal organs such as the liver, pancreas and bowel...
Largest Full Face Transplant Is Completed published
Thu, 29 Mar 2012 00:00:00 PDT
A team at R. Adams Cowley Shock Trauma Center at the University of Maryland Medical Center, completed a 36 hour operation to replace an entire patient's face, including teeth, both jaws and tongue. The procedure represents the largest face transplant on record. The transplant team was led by Eduardo D. Rodriguez, M.D., D.D.S...
The Most Extensive Full Face Transplant To Date Completed By University Of Maryland published
Wed, 28 Mar 2012 03:00:00 PDT
The University of Maryland has released details of the most extensive full face transplant completed to date, including both jaws, teeth, and tongue...
Liver Cancer Patients Less Likely To Die On Wait List Than Candidates Without Carcinomas published
Mon, 26 Mar 2012 00:00:00 PDT
New research shows increasing disparity in mortality among candidates with and without hepatocellular carcinoma (HCC) who are on the waiting list for liver transplantation...
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