Breaking news on muscular_dystrophy
Rochester Leads International Effort To Improve Muscular Dystrophy Treatment published
Sat, 04 Sep 2010 01:00:00 PDT
A large international study aimed at improving the care of muscular dystrophy patients worldwide is being launched by physicians, physical therapists, and researchers at the University of Rochester Medical Center. Neurologist Robert "Berch" Griggs, M.D., is heading the study of treatments for Duchenne muscular dystrophy, the most common form of the disease that affects children...
Functional Motor Neuron Subtypes Generated From Embryonic Stem Cells published
Sat, 04 Sep 2010 00:00:00 PDT
Scientists have devised a method for coaxing mouse embryonic stem cells into forming a highly specific motor neuron subtype. The research, published by Cell Press in the September 3rd issue of the journal Cell Stem Cell, provides new insight into motor neuron differentiation and may prove useful for devising and testing future therapies for motor neuron diseases...
Cause Of Lou Gehrig's Disease, Amyotrophic Lateral Sclerosis (ALS) Linked To Chromosome Nine published
Tue, 31 Aug 2010 01:00:00 PDT
Two substantial studies, and articles published by The Lancet Neurology have confirmed that variations to the genes located on chromosome number nine may contribute to the development of front temporal dementia and also ALS, amyotrophic lateral sclerosis which is commonly known as Lou Gehrig's Disease...
Charity Millions 'go To Fundraising Companies' - Muscular Dystrophy Campaign Comment, UK published
Mon, 30 Aug 2010 03:00:00 PDT
Please find below a comment from the Muscular Dystrophy Campaign following the story covered by Newsnight regarding fees paid to professional fundraising officers...
New Genetic Risk Factor For Lou Gehrig's Disease Identified By University Of Pennsylvania-Led Study published
Sat, 28 Aug 2010 00:00:00 PDT
An international study led by biologists and neuroscientists from the University of Pennsylvania has identified a new genetic risk factor for amyotrophic lateral sclerosis, commonly known as ALS or Lou Gehrig's disease...
In Mouse Model Of Inherited ALS, Neuron-Damaging Mechanism Discovered published
Sat, 28 Aug 2010 00:00:00 PDT
New research uncovers what may be a primary neuron-damaging insult that occurs in an inherited form of a devastating neurodegenerative disorder. The study, published by Cell Press in the journal Neuron, describes a critical mechanistic link between a mutant protein and disease pathogenesis in an animal model of amyotrophic lateral sclerosis (ALS)...
$7 Million Grant Designates Nationwide Children's As Wellstone Muscular Dystrophy Cooperative Research Center published
Fri, 27 Aug 2010 04:00:00 PDT
A $7 million grant from the National Institutes of Health (NIH) will help researchers at Nationwide Children's Hospital translate new scientific findings and technological developments into novel treatments for the muscular dystrophies. The grant designates Nationwide Children's Hospital as a Paul D...
Acceleron Pharma Receives FDA Orphan Designation For ACE-031 For The Treatment Of Duchenne Muscular Dystrophy published
Sun, 22 Aug 2010 00:00:00 PDT
Acceleron Pharma, Inc...
Biogen Idec And Knopp Neurosciences Announce License Agreement For Late-Stage ALS Drug Candidate published
Sat, 21 Aug 2010 02:00:00 PDT
Biogen Idec (NASDAQ: BIIB) and Knopp Neurosciences announced they have entered into an exclusive, worldwide license agreement under which Biogen Idec will develop and commercialize KNS-760704 (dexpramipexole) for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and potentially other indications...
Discovery Opens Door To Therapeutic Development For FSH Muscular Dystrophy published
Sat, 21 Aug 2010 00:00:00 PDT
Scientists are closer to understanding what triggers muscle damage in one of the most common forms of muscular dystrophy, called facioscapulohumeral muscular dystrophy (FSHD). FSHD affects about 1 in 20,000 people, and is named for progressive weakness and wasting of muscles in the face, shoulders and upper arms. Although not life-threatening, the disease is disabling...
Add To Human Genome's Greatest Hits, DNA Culprits That Cause FSH Muscular Dystrophy Found published
Sat, 21 Aug 2010 00:00:00 PDT
The Muscular Dystrophy Association today heralds a landmark muscular dystrophy advance by an international study team of scientists and physicians from the Netherlands, United States, France and Spain. Led by MDA-grantee Silvère van der Maarel, Ph.D...
International Research Team Closes In On Cause Of Common Form Of Muscular Dystrophy published
Fri, 20 Aug 2010 04:00:00 PDT
An international team of researchers that includes investigators from Fred Hutchinson Cancer Research Center has made a critical advance in determining the cause of a common form of muscular dystrophy known as facioscapulohumeral dystrophy, or FSHD. They have identified a DNA sequence in individuals with FSHD that causes a gene called DUX4 to be more active...
MDA Awards $14.1 Million In New Grants To Advance Treatments For Muscle And Nerve Diseases published
Thu, 19 Aug 2010 03:00:00 PDT
The Muscular Dystrophy Association, which has invested almost $39 million in 2010 in worldwide research seeking treatments and cures for muscle diseases, announced that it has awarded $14.1 million in new grants...
Head Trauma In Pro Athletes Linked To Motor Neuron Disease published
Wed, 18 Aug 2010 03:00:00 PDT
Professional athletes with repetitive head trauma and possibly others with a history of head injuries many years previously may be prone the development of a motor neuron disease similar to amyotrophic lateral sclerosis (ALS or "Lou Gehrig's disease"), reports a study in the September Journal of Neuropathology & Experimental Neurology, official journal of the American Associati...
Lithium Shows No Benefit For People With ALS published
Thu, 12 Aug 2010 01:00:00 PDT
A new study has found that the drug lithium is not effective in treating people with amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease. The research is published in the August 11, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology...
Parent Project Muscular Dystrophy Awards $600K To Nationwide Children's Hospital For Gene Therapy Study published
Wed, 11 Aug 2010 01:00:00 PDT
Parent Project Muscular Dystrophy (PPMD), the largest non-profit organization in the United States focused on finding a cure for Duchenne muscular dystrophy (Duchenne), announced that PPMD will award a $600,000 grant to Nationwide Children's Hospital in Columbus, Ohio to conduct clinical testing of a promising gene therapy technique for muscle disease. Investigators, led by Jerry Mendell, M...
Disappointing Results From BioMarin's Utrophin Clinical Trial For Duchenne published
Mon, 09 Aug 2010 05:00:00 PDT
BioMarin has announced disappointing results from the Phase I clinical trial of 'BMN-195' and it has halted development of the compound. BMN-195 is an oral drug with the potential to increase the amount of the protein utrophin in the muscles. Utrophin is thought to be able to substitute for the missing dystrophin protein in boys with Duchenne muscular dystrophy...
FDA Fast Track Designation Gained For ACE-031 For Duchenne Muscular Dystrophy published
Mon, 09 Aug 2010 05:00:00 PDT
Acceleron Pharma has gained FDA Fast Track designation for ACE-031 which will help to speed its journey through the drug approval process. ACE-031 is a substance that may be able to increase the size and strength of muscle and has the potential to treat a range of muscle diseases. A clinical trial in boys with Duchenne muscular dystrophy was started in May this year in Canada...
Concerns Raised Over Prime Minister's Remarks On Social Housing Tenancies, UK published
Mon, 09 Aug 2010 05:00:00 PDT
The Muscular Dystrophy Campaign has warned that proposals to introduce fixed terms for social housing tenancies may force some people with severe disabilities out of homes that have been adapted for them into inaccessible privately rented accommodation...
Muscular Dystrophy Campaign Responds To Government Welfare Reform Plans published
Wed, 04 Aug 2010 01:00:00 PDT
The Muscular Dystrophy Campaign welcomes the intention in the 21st Century Welfare consultation paper to simplify the complex benefits system, and to make the process more efficient...
New Approach Which Can Help To Predict Neurodegenerative Diseases published
Tue, 27 Jul 2010 01:00:00 PDT
New investigations, initiated by research workers at CIC bioGUNE and led by Dr. Aitor Hierro, have opened possibilities for making progress in the knowledge and prediction of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS), according to the journal of The Proceedings of the National Academy of Sciences of the United States of America...
AVI BioPharma Announces Presentations On Exon Skipping Drug AVI-4658 For Treatment Of Duchenne Muscular Dystrophy published
Mon, 19 Jul 2010 03:00:00 PDT
AVI BioPharma, Inc. (NASDAQ: AVII), a developer of RNA-based drugs, announced upcoming presentations on AVI-4658, the Company's exon skipping therapy for the treatment of Duchenne muscular dystrophy, at the XII International Congress on Neuromuscular Diseases taking place July 17-22, 2010 in Naples, Italy...
New Way To Grow Adult Stem Cells In Culture May Lead To Treatment For Muscular Dystrophy published
Sat, 17 Jul 2010 00:00:00 PDT
Researchers at the Stanford University School of Medicine have developed a technique they believe will help scientists overcome a major hurdle to the use of adult stem cells for treating muscular dystrophy and other muscle-wasting disorders that accompany aging or disease: They've found that growing muscle stem cells on a specially developed synthetic matrix that mimics the ela...
AVI BioPharma Opens Investigational New Drug (IND) Application For AVI-4658 In Duchenne Muscular Dystrophy published
Thu, 08 Jul 2010 01:00:00 PDT
AVI BioPharma, Inc. (NASDAQ: AVII), a developer of RNA-based therapeutics, announced that following review by the U.S. Food and Drug Administration the Company's Investigational New Drug (IND) application for AVI-4658 is open...
Emerging Questions About The Mechanisms That Control Muscle published
Tue, 29 Jun 2010 02:00:00 PDT
There are major shifts underway in understanding the physiological mechanisms that control muscle contraction, a field that has been the focus of intense research for centuries...
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