communicate and influence each other, even when they are located far away from each other...

Cancer Genomics: Special Issue Published By Genome Research published Fri, 03 Feb 2012 01:00:00 PST
Genome Research publishes online and in print a special issue entitled, "Cancer Genomics," highlighting insights gained form cutting-edge genomic and epigenomic analyses of cancer...

Scientists Analysing The Release Of Genetically Modified Insects Into The Environment Find The Available Scientific Information Can Be Misleading published Fri, 03 Feb 2012 01:00:00 PST
While genetically modified plants have already been introduced into the wild on a large scale in some parts of the world, the release of genetically modified animals is still at a relatively early stage...

Circular RNAs More Common Than Previously Thought published Fri, 03 Feb 2012 00:00:00 PST
In the classical model of gene expression, the genetic script encoded in our genomes is expressed in each cell in the form of RNA molecules, each consisting of a linear string of chemical "bases"...

Chaos In The Cell's Command Center published Fri, 03 Feb 2012 00:00:00 PST
A defective operating system is never a good thing. Like computers, our cells depend on operating systems to drive normal functions. Gene expression programs comprise the software code our cells rely on, with each cell type controlled by its own program. Corrupted programs can trigger disease...

Dyslexia-Linked Genetic Variant Decreases Midline Crossing Of Auditory Pathways published Fri, 03 Feb 2012 00:00:00 PST
Finnish scientists have found that a rare dyslexia-linked genetic variant of the ROBO1 gene decreases normal crossing of auditory pathways in the human brain. The weaker the expression of the gene is, the more abnormal is the midline crossing. The results link, for the first time, a dyslexia-susceptibility gene to a specific sensory function of the human brain...

Osteoporosis Drug Complications Linked To Genetic Factors published Thu, 02 Feb 2012 10:00:00 PST
According to a study published in the online version of the journal The Oncologist, a genetic variation that increases the risk of individuals who take bisphosphonates, developing serious necrotic jaw bone lesions, has been identified by researchers at the Columbia University College of Dental Medicine...

A New Genetic Subtype Of Lung Cancer Defined published Thu, 02 Feb 2012 01:00:00 PST
A report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S...

Hyperconnectivity In Brain's Hearing Center Caused By Gene Mutation In Autism published Thu, 02 Feb 2012 01:00:00 PST
New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound...

How Genes Are Affected By Weightlessness - A Fly's Perspective published Thu, 02 Feb 2012 00:00:00 PST
On Earth all biology is subjected to gravity. Some biological systems require gravity for correct orientation (geotropism: plants grow up, roots grow down). In the absence of gravity even human biology is affected: astronauts lose bone density at 1-2% a month rather than the usual 1-2% a year on Earth. But the effects of gravity on cellular processes are less well understood...

Shedding Light On Nonalcoholic Fatty Liver Disease: Gene Mutation Linked To Accumulation Of Fat, Other Lipids In Liver published Thu, 02 Feb 2012 00:00:00 PST
A team of scientists from the University of Utah and the University of California at San Francisco has discovered that the mutation of a gene encoding a ketone body transporter triggers accumulation of fat and other lipids in the livers of zebrafish. This discovery, published in the Feb...

Liquid Lasers May Better Detect Genes Linked To Cancer published Thu, 02 Feb 2012 00:00:00 PST
Using a liquid laser, University of Michigan researchers have developed a better way to detect the slight genetic mutations that might predispose a person to a particular type of cancer or other diseases. Their results are published in the current edition of the German journal Angewandte Chemie. This work could advance understanding of the genetic basis of diseases...

Defects In The Packaging Of DNA In Malignant Brain Tumors published Wed, 01 Feb 2012 00:00:00 PST
Glioblastomas grow extremely aggressively into healthy brain tissue and, moreover, are highly resistant to radiation therapy and chemotherapy. Therefore, they are regarded as the most malignant type of brain tumor. Currently available treatment methods are frequently not very effective against this type of cancer...

Metabolic Errors Affect DNA published Tue, 31 Jan 2012 09:00:00 PST
Cells rely on purines, which are types of molecules that make up half of the DNA and RNA building blocks, and are a key component of the chemicals that store a cell's energy in order to perform many vital functions. The purine supply is strictly controlled by the cells, with any disruption likely to cause serious potential consequences...

Research Scientists Illuminate Cancer Cells' Survival Strategy During Dangerous Dissemination published Tue, 31 Jan 2012 00:00:00 PST
A team led by scientists at The Scripps Research Institute has discovered key elements of a strategy commonly used by tumor cells to survive when they spread to distant organs. The finding could lead to drugs that could inhibit this metastasis in patients with tumors...

SUMO-Snipping Protein Plays Crucial Role In T And B Cell Development published Tue, 31 Jan 2012 00:00:00 PST
When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in Molecular Cell...

Cerebral Palsy Linked With Genetic Abnormalities published Mon, 30 Jan 2012 10:00:00 PST
Researchers at Geisinger Health System have found that genetic abnormalities may be the cause for the majority of cerebral palsy (CP) cases, a group of disorders that can involve the brain and nervous system functions, such as seeing, movement, hearing, thinking, and learning, rather than a difficult birth or other perinatal factors. CP is the most prevalent physical disability of childhood...

Study Of Genetic Regulation Of Metabolomic Biomarkers - Paths To Cardiovascular Diseases And Type 2 Diabetes published Mon, 30 Jan 2012 01:00:00 PST
In a study into the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that take part in various chemical reactions of human body...

Mutations Tied To Aggressive Childhood Brain Tumors Revealed By Cancer Sequencing Initiative published Mon, 30 Jan 2012 01:00:00 PST
Researchers studying a rare, lethal childhood tumor of the brainstem discovered that nearly 80 percent of the tumors have mutations in genes not previously tied to cancer. Early evidence suggests the alterations play a unique role in other aggressive pediatric brain tumors as well. The findings from the St...

How Bacteria Behind Serious Childhood Disease Evolve To Evade Vaccines published Mon, 30 Jan 2012 01:00:00 PST
Genetics has provided surprising insights into why vaccines used in both the UK and US to combat serious childhood infections can eventually fail. The study, published in Nature Genetics, which investigates how bacteria change their disguise to evade the vaccines, has implications for how future vaccines can be made more effective...

Stress-Induced Genomic Instability Facilitates Rapid Cellular Adaption In Yeast published Mon, 30 Jan 2012 01:00:00 PST
Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions...

How New Viruses Evolve, And In Some Cases, Become Deadly published Mon, 30 Jan 2012 00:00:00 PST
Researchers at Michigan State University (MSU) have demonstrated how a new virus evolves, shedding light on how easy it can be for diseases to gain dangerous mutations. The findings appear in the journal Science. The scientists showed for the first time how the virus called "Lambda" evolved to find a new way to attack host cells, an innovation that took four mutations to accomplish...

Tracking The Birth Of An Evolutionary Arms Race Between HIV-Like Viruses And Primate Genomes published Sun, 29 Jan 2012 00:00:00 PST
Using a combination of evolutionary biology and virology, scientists at Fred Hutchinson Cancer Research Center have traced the birth of the ability of some HIV-related viruses to defeat a newly discovered cellular-defense system in primates. The research, led by Michael Emerman, Ph.D., a member of the Hutchinson Center's Human Biology and Basic Sciences Division, and Harmit Malik, Ph.D...

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