Breaking news on epilepsy
Keppraź Approved By FDA For Childhood Seizures published
Fri, 27 Jan 2012 09:00:00 PST
In the U.S., Keppraź has been approved as adjunctive therapy for partial onset seizures in adults and children aged four years and older with epilepsy. However the UCB recently announced that the U.S. Food and Drug Administration (FDA) has now approved to lower the age restriction to include infants from the age of one month and older with epilepsy. Professor Dr...
Neurologically Impaired Children Dependent On Children's Hospitals: Researchers Point To Need For Better Care Coordination In The Community published
Thu, 19 Jan 2012 01:00:00 PST
Because of care advances, more infants and children with previously lethal health problems are surviving. Many, however, are left with lifelong neurologic impairment. A Children's Hospital Boston study of more than 25 million pediatric hospitalizations in the U.S...
A Step Closer To Unlocking A Mystery That Causes Epileptic Seizures In Babies published
Wed, 18 Jan 2012 02:00:00 PST
Benign familial infantile epilepsy (BFIE) has been recognised for some time as infantile seizures, without fever, that run in families but the cause has so far eluded researchers. However clinical researchers at the University of Melbourne and Florey Neurosciences Institute and molecular geneticists at the University of South Australia have discovered a gene...
Guidelines Stress Caution When Combining Anti-Epileptic, HIV Drugs published
Sat, 07 Jan 2012 00:00:00 PST
New guidelines from the American Academy of Neurology will help physicians better choose seizure drugs for people on HIV/AIDS medication, avoiding deadly drug interactions and preventing critical anti-HIV drugs from becoming less effective, possibly leading to a more virulent strain of the disease...
Epilepsy And Violent Crime Not Linked published
Thu, 05 Jan 2012 10:00:00 PST
According to a large Swedish investigation published in PloS Medicine, epilepsy is not directly linked to an increased risk of committing violent crime. Although, individuals who previously experienced traumatic brain injury (TBI) have an increased risk of committing violent crime...
Findings In Songbirds May Have Important Implications For Brain Degeneration In Humans published
Thu, 05 Jan 2012 00:00:00 PST
Colin Saldanha, a biology professor at American University in Washington, D.C., has always been intrigued by the hormone estrogen. Specifically, how the hormone that does so much (for example, it promotes sexual behavior in women but can also increase susceptibility to seizures) does not cause major cross circuit meltdowns...
Marinus Pharmaceuticals Experimental Epilepsy Treatment Shows Promise In Open-Label Extension Study published
Sun, 01 Jan 2012 01:00:00 PST
Marinus Pharmaceuticals, Inc., a specialty pharmaceutical company, announced that its neurosteroid ganaxolone which is currently under study for the treatment of partial onset seizures (POS), reported positive data in the open-label extension follow up to the company's Phase 2 clinical trial. The data reflects the replication of the effects seen in the double-blind study...
An Answer To A Mysterious Movement Disorder Discovered In The Genome published
Wed, 28 Dec 2011 00:00:00 PST
Children with a rather mysterious movement disorder can have hundreds of attacks every day in which they inexplicably make sudden movements or sudden changes in the speed of their movements. New evidence reported in an early online publication from the January 2012 inaugural issue of Cell Reports, the first open-access journal of Cell Press, provides an answer for them...
Childhood Disorder Called PKD Linked To Genetic Mutations published
Tue, 20 Dec 2011 00:00:00 PST
A large, international team of researchers led by scientists at the University of California, San Francisco has identified the gene that causes a rare childhood neurological disorder called PKD/IC, or "paroxysmal kinesigenic dyskinesia with infantile convulsions," a cause of epilepsy in babies and movement disorders in older children...
Superior Drug Combo For Difficult-To-Control Epilepsy published
Sat, 17 Dec 2011 00:00:00 PST
A combination of two common drugs, lamotrigine and valproate, is more effective in treating difficult-to control epilepsy than other anti-epileptic regimens, according to a University of Washington report published online this week in Neurology, the journal of the American Academy of Neurology...
Epilepsy In Children - Adverse Events of Invasive EEG, Study published
Thu, 15 Dec 2011 08:00:00 PST
According to an investigation led by Dr...
Seizure Damage Reversed In Rats By Inhibitory Drug Targeting Neurologic Pathways published
Thu, 15 Dec 2011 00:00:00 PST
About half of newborns who have seizures go on to have long-term intellectual and memory deficits and cognitive disorders such as autism, but why this occurs has been unknown...
Electrical Activity In The Brain Likened To An Orchestra published
Tue, 13 Dec 2011 02:00:00 PST
Researchers at the Norwegian University of Life Sciences (UMB) have developed a new method for detailed analyses of electrical activity in the brain. The method, recently published in Neuron, can help doctors and researcher to better interpret brain cell signals...
A More Ethical Way To Compare Epilepsy Treatments published
Tue, 06 Dec 2011 00:00:00 PST
Epilepsy drug-switching study shows that using more ethical control groups could be the way forward for testing both drug efficacy and safety For the first time, a new research methodology recently approved by the Food and Drug Administration has been used to demonstrate that converting patients from one anti-epileptic drug to another - in this case, lamotrigine extended-rel...
Causative Gene May Differ Among Patients With Dravet Syndrome published
Sun, 04 Dec 2011 01:00:00 PST
Dravet syndrome is a severe genetic epilepsy that appears early in life. About 75 percent of cases can be attributed to mutations in the SCN1A gene encoding the sodium channel NaV1.1. The remaining patients with this syndrome are without a definitive molecular genetic diagnosis...
Phase III Progesterone Therapy Trial For Women With Epilepsy Has Favorable Outcome published
Sat, 03 Dec 2011 01:00:00 PST
Seizures in women of childbearing age commonly show patterns of exacerbation that involve hormones as a factor. Investigators reported the favorable outcome of a multicenter randomized, double-blinded, placebo-controlled phase III clinical trial of progesterone therapy in reducing these perimenstrually exacerbated (catamenial) seizures...
Research Documents Seizure Trends In Women With Catamenial Epilepsy published
Sat, 03 Dec 2011 00:00:00 PST
In women of childbearing age with epilepsy, seizure exacerbation may occur either at the time of menstruation or ovulation...
Long Term Older Antiepileptic Drug Usage Linked To Hardening Of Arteries published
Wed, 16 Nov 2011 05:00:00 PST
According to new research published in Epilepsia, the journal of the International League Against Epilepsy (ILAE), patients with epilepsy who were treated with older generation antiepileptic drugs (AEDs) for extended periods may be at increased risk for developing atherosclerosis, a common disorder known as hardening of the arteries...
Long-Term Antiepileptic Drug Therapy And Vascular Risk published
Wed, 16 Nov 2011 02:00:00 PST
New research reveals that patients with epilepsy who were treated for extended periods with older generation antiepileptic drugs (AEDs) may be at increased risk for developing atherosclerosis, a common disorder known as hardening of the arteries...
Ultrathin Flexible Brain Implant Offers Unique Look At Seizures published
Mon, 14 Nov 2011 01:00:00 PST
Researchers funded by the National Institutes of Health have developed a flexible brain implant that could one day be used to treat epileptic seizures. In animal studies, the researchers used the device - a type of electrode array that conforms to the brain's surface - to take an unprecedented look at the brain activity underlying seizures...
Expert Calls For Increased Awareness And Research Of Sudden Death In Patients With Epilepsy published
Sun, 13 Nov 2011 00:00:00 PST
Over time, epileptic seizures can lead to major health issues, including significant cognitive decline and even death, warns Orrin Devinsky, MD, professor, Departments of Neurology, Neurosurgeryand Psychiatryat NYU Langone Medical Center...
Brain Stimulator Shown To Reduce 'Untreatable' Epileptic Seizures published
Wed, 09 Nov 2011 02:00:00 PST
Brain stimulation, already approved by the U.S. Food and Drug Administration for the treatment of Parkinson's disease and essential tremor, has now been shown to offer significant relief to patients with intractable seizures for whom drugs and other treatments have not worked...
Drug Prevents Cerebral Cavernous Malformation In Mice; Could Replace Surgery published
Sun, 30 Oct 2011 00:00:00 PST
A drug treatment has been proven to prevent lesions from cerebral cavernous malformation - a brain blood vessel abnormality that can cause bleeding, epilepsy and stroke - for the first time in a new study...
FDA Approves Onfi To Treat Severe Type Of Seizures published
Tue, 25 Oct 2011 09:00:00 PST
As of 21st Oct Onfi (clobazam) tablets are FDA (U.S. Food and Drug Administration) approved as an add on treatment for seizures caused by Lennox-Gastaut syndrome in adults and children aged 2 years and older. The disease effects fewer than 200,000 people in the United States so it was granted what as known as "orphan status". Russell Katz, M.D...
Neurons Associated With Epilepsy Rescued By Optimal Modulation Of Ion Channels published
Thu, 20 Oct 2011 01:00:00 PST
New research successfully reverses epilepsy-associated pathology by using a sophisticated single-cell modeling paradigm to examine abnormal cell behavior and identify the optimal modulation of channel activity...
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