Breaking news on crohns
Traveling With Inflammatory Bowel Disease published
Fri, 27 Jan 2012 00:00:00 PST
Inflammatory bowel disease (IBD) travelers have an increased risk of illness during trips to industrialized countries, but not to developing or tropical regions, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association...
Less Risk Of Inflammatory Bowel Disease In Warmer Climates published
Mon, 16 Jan 2012 10:00:00 PST
A long-term U.S. study published online in GUT has shown that living in sunnier climates may lower the chances of developing inflammatory bowel disease, especially in those aged 30 years or over. The researchers' findings, which support earlier European research, could potentially lead to new therapies and preventive measures...
IBD Emerges As A Global Disease published
Fri, 06 Jan 2012 00:00:00 PST
The incidence and prevalence of inflammatory bowel disease (IBD) are increasing with time and in different regions around the world, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association...
Endometriosis Raises Risk OF Inflammatory Bowel Disease published
Sat, 24 Dec 2011 00:00:00 PST
About one in ten women of child-bearing age suffers from endometriosis, a fairly common condition in which cells from the lining of the uterus grow in other areas of the body. According to a study published in Gut, women with endometriosis are almost twice as likely to develop inflammatory bowel disease compared to other females...
Why Does African Naked Mole-Rat Not Feel Pain With Acid published
Thu, 22 Dec 2011 10:00:00 PST
A new study has found out why the African naked mole-rat (Heterocephalus glaber) experiences no pain when exposed to acid. The African naked mole-rat is one of the most unusual mammals in the world. They live in large groups underground in dark narrow burrows where carbon dioxide (CO2) levels are extremely high...
Team Pinpoints Amino Acid Variation In Immune Response Gene Linked With Ulcerative Colitis published
Mon, 19 Dec 2011 00:00:00 PST
The association between the inflammatory bowel disease ulcerative colitis and a gene that makes certain cell surface proteins has been pinpointed to a variant amino acid in a crucial binding site that profoundly influences immune response to antigens, including gut bacteria, reports a team of researchers at the University of Pittsburgh, Cleveland Clinic, Carnegie Mellon Univers...
Personalized Treatment For Crohn's Disease A Step Closer Following Gene Mapping published
Mon, 12 Dec 2011 00:00:00 PST
Three new locations for Crohn's Disease genes have been uncovered by scientists at UCL using a novel gene mapping approach. The complex genetic and environmental causes of Crohn's Disease (CD) have long been difficult to untangle. CD, a type of Inflammatory Bowel Disease that affects about 100 to 150 people per 100,000 in Europe, is characterised by inflammation in the gastrointestinal tract...
Inflammatory Cues Modulate Goblet Cell Products Important For Intestinal Barrier Function published
Mon, 05 Dec 2011 01:00:00 PST
In a paper published in the December 2011 issue of Experimental Biology and Medicine, a team of scientists at the University of Illinois, Urbana-Champaign led by Rex Gaskins, PhD have demonstrated that both microbial and host inflammatory factors modulate sulfomucin production in a human cell line, LS174T, that models intestinal goblet cells...
Anti-Inflammatory Polyphenols Discovered In Apple Peels published
Thu, 01 Dec 2011 01:00:00 PST
Here's another reason why "an apple a day keeps the doctor away" - according to new research findings published in the Journal of Leukocyte Biology*, oral ingestion of apple polyphenols (antioxidants found in apple peels) can suppress T cell activation to prevent colitis in mice...
An IBS Patient's Interpretation Of Symptom Severity Is Affected By Psychological Factors published
Thu, 24 Nov 2011 00:00:00 PST
A patient's viewpoint of the severity of irritable bowel syndrome (IBS) symptoms can be influenced not only by physical symptoms of IBS but broader psychological problems, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association...
Inflammatory Bowel Disease Associated With Increased Skin Cancer Risk published
Wed, 23 Nov 2011 00:00:00 PST
Certain patients with inflammatory bowel disease (IBD) may have an increased risk of skin cancer, which is intensified by the use of immunosuppressant medications , according to two new studies in Gastroenterology, the official journal of the American Gastroenterological Association. Immunosuppressants are commonly used in the treatment of IBD...
Some Colon Tumors Caused By Common Bacteria Altering Peroxide-Producing Gene published
Tue, 08 Nov 2011 00:00:00 PST
Working with lab cultures and mice, Johns Hopkins scientists have found that a strain of the common gut pathogen Bacteroides fragilis causes colon inflammation and increases activity of a gene called spermine oxidase (SMO) in the intestine...
Stopping Autoimmunity In The NIK Of Time; CX3CR1: A Protein With Guts published
Thu, 03 Nov 2011 00:00:00 PST
IMMUNOLOGY: Stopping autoimmunity in the NIK of time Immune cells known as T cells play a key role in ridding the body of dangerous microbes. However, if they are not kept under control properly they can attack the body's own tissues and cells and cause autoimmunity...
Antibiotic-Associated Diarrhea Responds To Probiotics published
Tue, 01 Nov 2011 04:00:00 PST
'Good bugs' look promising as anti-inflammatory agent for patients with ulcerative colitis, psoriasis, chronic fatigue syndrome In four different studies presented at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC, researchers explored the effectiveness of probiotics for antibiotic-associated diarrhea; as an anti-inflammat...
Effective Treatment For C. difficile, Inflammatory Bowel Disease - Fecal Microbiota Transplants published
Tue, 01 Nov 2011 04:00:00 PST
Growing evidence for the effectiveness of fecal microbiota transplants as a treatment for patients with recurrent bouts of Clostridium difficile (C.difficile) associated diarrhea is presented in three studies -- including a long-term follow-up of colonoscopic fecal microbiota transplant (FMT) for recurrent C...
Latitude Variation In Incidence Of Chronic Digestive Diseases Confirmed By US Research published
Tue, 01 Nov 2011 03:00:00 PST
Investigators explore potential role of UV light exposure and vitamin D in Crohn's therapy New research points to a potential role for UV light exposure and vitamin D levels in chronic digestive conditions; Crohn's disease, a serious inflammatory condition in the small intestine; and ulcerative colitis (UC), which similarly affects the colon...
Although Social Media Has A Role In Delivery Of Healthcare, Patients Should Proceed With Caution published
Tue, 01 Nov 2011 03:00:00 PST
Social networking sites like Facebook and YouTube can be powerful platforms to deliver and receive healthcare information, especially for patients and caregivers who are increasingly going online to connect and share experiences with others with similar medical issues or concerns...
Antigen-Specific Treg Cells For Crohn's Disease Treatment - Trial published
Mon, 31 Oct 2011 08:00:00 PST
TxCell presents final positive results of the phase I/II clinical trial with antigen-specific Treg cells in Crohn's disease. At the United European Gastroenterology Week (UEGW) in Stockholm, TxCell SA presented the final positive results of its phase I/II study of OvaSave ® developed for the treatment of patients with severe chronic active Crohn's disease (CATS-1)...
Treating Inflammatory Bowel Disease With A Probiotic published
Fri, 21 Oct 2011 00:00:00 PST
Scientists have been unclear for some time about how most probiotics work. A new study has found a scientific 'design' for a probiotic that could be used to treat inflammatory bowel disease (IBD), such as Crohn's disease. The research by academics at the University of Bristol's School of Veterinary Sciences and the School of Clinical Medicine is published online in the journal PLoS ONE...
Inflammatory Bowel Disease Patients Have Higher Risk Of Post Operative DVT And Pulmonary Embolism published
Tue, 18 Oct 2011 05:00:00 PST
A study published Online First by Archives of Surgery, one of the JAMA/Archives journals reveals that patients with inflammatory bowel disease (IBD) undergoing surgery may be more susceptible to develop deep vein thrombosis (DVT) or pulmonary embolism (PE) following surgical procedures...
Diagnostic Tool Distinguishes Intestinal Inflammation From Fibrosis, Could Aid Efficient, Timely Treatment For Crohn's Disease published
Mon, 17 Oct 2011 01:00:00 PST
It's difficult for doctors to tell whether a patient with Crohn's disease has intestinal fibrosis, which requires surgery, or inflammation, which can be treated with medicine. A new imaging method might make that task easier, according to a U-M-led study...
Comparison Between Narrow Band Imaging And Chromoendoscopy For The Detection Of Dysplasia In IBD Patients published
Fri, 14 Oct 2011 00:00:00 PST
A new study from Spain finds that narrow band imaging appears to be a less time-consuming and equally effective alternative to chromoendoscopy for the detection of dysplasia (abnormal growths) in patients with long-standing inflammatory bowel disease...
Detecting Pre-Cancerous Colon Cells published
Wed, 12 Oct 2011 03:00:00 PST
After demonstrating that light accurately detected pre-cancerous cells in the lining of the esophagus, Duke University bioengineers turned their technology to the colon and have achieved similar results in a series of preliminary experiments. This technology could be a non-invasive way for physicians to detect abnormal cells, or dysplasia, which have the potential of turning cancerous...
Predicting Prognosis In Patients With Inflammatory Bowel Disease published
Tue, 27 Sep 2011 02:00:00 PST
Crohn disease (CD) and ulcerative colitis (UC) are the two most common forms of inflammatory bowel disease, affecting approximately 1 million people in the US. The severity of the symptoms and the frequency with which they recur varies widely among patients...
Blocking Inflammation Could Lead To Tailored Medical Treatments published
Wed, 21 Sep 2011 01:00:00 PST
By using a mouse model of inflammation researchers at the University of Calgary have discovered a new class of molecules that can inhibit the recruitment of some white blood cells to sites of inflammation in the body. A provisional patent has been filed on these molecules by Innovates Calgary...
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