Breaking news on Clinical trials
Drug effects hidden by poor placebo reporting published
Tue, 01 Oct 2019 03:00:00 PDT
According to the authors of a new study, poor reporting of placebo interventions has the potential to alter the conclusions of medical trials.
Alzheimer's: Head device reduces memory loss in 7 out of 8 people published
Fri, 20 Sep 2019 09:00:00 PDT
A clinical trial has found that an innovative electromagnetic therapy device significantly reduced memory loss in seven out of the eight participants.
Common antidepressant may ease anxiety more quickly than depression published
Fri, 20 Sep 2019 08:00:00 PDT
A trial of sertraline in primary care found that the common antidepressant reduced anxiety symptoms in 6 weeks with some easing of depression at 12 weeks.
Cancer: Why drug testing needs to improve published
Wed, 18 Sep 2019 07:00:00 PDT
A new study finds that many new cancer drugs may not work in the way their developers think they do, which could have implications for their effectiveness.
OCD: Deep magnetic stimulation may help where other therapies fail published
Mon, 09 Sep 2019 07:00:00 PDT
A new trial found that deep transcranial magnetic stimulation may help ease cases of obsessive-compulsive disorder that do not respond to other treatments.
Investigating 'spin' in scientific journals published
Sat, 10 Aug 2019 03:00:00 PDT
Do researchers use spin to enhance their findings? A recent investigation into psychology and psychiatry journals concludes that they do.
Nonalcoholic fatty liver disease: New drug proves 'safe' and effective published
Tue, 30 Jul 2019 07:00:00 PDT
A double-blind, placebo-controlled randomized clinical trial finds the right dosage at which a drug 'safely' treats nonalcoholic fatty liver disease.
Has safety commission misled the public about aspartame? published
Wed, 24 Jul 2019 07:00:00 PDT
Researchers from the United Kingdom cast serious doubts on official reports concluding that aspartame, the most common artificial sweetener, is safe.
Alzheimer's: Common gene explains why some drugs fail published
Sun, 21 Jul 2019 03:00:00 PDT
A new study helps to explain why some Alzheimer’s drugs work in some people but not in others, and why some yet may succeed in animals but not in humans.
Can a cannabis-based drug treat cannabis dependence? published
Wed, 17 Jul 2019 07:00:00 PDT
Researchers have found a cannabis-based replacement therapy that effectively treats cannabis dependence, a new clinical trial suggests.
New drug relieves acute migraine in clinical trial published
Fri, 12 Jul 2019 08:00:00 PDT
The results of a large phase III trial show that the novel drug rimegepant can relieve pain and other symptoms of acute migraine with minimal side effects.
Why scientists are searching the ocean for new drugs published
Sat, 08 Jun 2019 00:00:00 PDT
Medical researchers are increasingly turning their attention to the ocean in their search for new drugs. In this Spotlight, we ask why.
In mice: Are animal studies relevant to human health? published
Fri, 24 May 2019 00:00:00 PDT
Scientists often use animal models such as mice and rats in biomedical research. But what can these studies tell us about human health?
Depression: Esketamine trial leaves 'more questions than answers' published
Thu, 23 May 2019 00:00:00 PDT
A clinical trial for intranasal esketamine found it effective and safe for severe depression, leading to an FDA approval. But is this the end of the road?
Novel Alzheimer's drug passes first phase of human testing published
Wed, 15 May 2019 09:00:00 PDT
A drug that tackles toxic protein buildup in Alzheimer's disease in a novel way has passed phase 1 of clinical trials, which tests safety in humans.
How plants from Mauritius could help fight cancer published
Mon, 06 May 2019 03:00:00 PDT
Research into the medicinal herbs of Mauritius shows that we may still have much to learn about the anticancer properties of many of the island plants.
Cancer: Highly personalized therapy can improve outcomes published
Tue, 23 Apr 2019 08:00:00 PDT
A new test-of-concept study suggests that using personalized combination therapy could improve the outcome for people with stubborn metastatic cancer.
Experimental drug may ease opioid withdrawal symptoms published
Sun, 14 Apr 2019 00:00:00 PDT
New research suggests that a drug that scientists initially developed to treat major depressive disorder may be an effective therapy for opioid addiction.
Dementia: Amyloid PET scans can improve diagnosis and care published
Wed, 03 Apr 2019 09:00:00 PDT
Using brain scans that can detect hallmarks of Alzheimer's could improve diagnosis and clinical care of people with dementia and mild cognitive impairment.
Surgery with ultrasound treats high blood pressure in trial published
Fri, 22 Mar 2019 08:00:00 PDT
A minimally invasive procedure that disables nerves leading to the kidneys maintained reduced blood pressure for 6 months with less prescribed medications.
Parkinson's: Study reveals how cancer drug reduces toxic protein in brain published
Wed, 13 Mar 2019 09:00:00 PDT
An analysis of trial results reveals the mechanism through which the cancer drug nilotinib increases brain dopamine in people with Parkinson's disease.
New brain stimulation therapy is effective against depression published
Tue, 12 Mar 2019 07:00:00 PDT
A pilot clinical trial has found that a new type of electrical stimulation therapy can be very effective in treating the symptoms of major depression.
New drug may stop sepsis from reaching major organs published
Sat, 09 Mar 2019 00:00:00 PDT
The results of a preclinical trial show that a new drug may stop sepsis, which is a potentially fatal condition, from progressing.
New treatment under trial could restore brain cells in Parkinson's published
Wed, 27 Feb 2019 07:00:00 PDT
A series of clinical trials have concluded that a new therapy, alongside a novel method of delivery, could be effective in treating Parkinson's disease.
New drug shows promise against several aggressive cancers published
Wed, 13 Feb 2019 00:00:00 PDT
Initial trials in humans find that a new drug, tisotumab vedotin, shows significant promise in treating stubborn tumors in several late-stage cancers.