Breaking news on cleft palate
New Mouse Model Could Lead To New Treatments And Prevention Strategies For Cleft Lip And Cleft Palate In Humans published
Wed, 30 Nov 2011 00:00:00 PST
Scientists at Weill Cornell Medical College used genetic methods to successfully repair cleft lips in mice embryos specially engineered for the study of cleft lip and cleft palate. The research breakthrough may show the way to prevent or treat the conditions in humans...
Risk For Two Birth Defects Affected By Overall Quality Of Pregnant Woman's Diet published
Tue, 04 Oct 2011 03:00:00 PST
The overall quality of a pregnant woman's diet is linked with risk for two types of serious birth defects, a new study from the Stanford University School of Medicine has shown. In the study, women who ate better before and during pregnancy gave birth to fewer infants with malformations of the brain and spinal cord, or orofacial clefts, such as cleft lip and cleft palate...
Two Brothers Born With Forms Of Cleft Lip And Palate Raises Awareness Of Condition And Risk Factors published
Wed, 08 Jun 2011 11:00:00 PST
Carter and Mason Osborne have a lot in common. Not only are they brothers who love to laugh, they also share one unique characteristic; they were born with forms of cleft lip and palate. Fortunately, the Osborne's have a team of nationally-recognized experts in the Cleft Lip and Palate Center at Nationwide Children's Hospital to help with their sons' overall treatment and care...
Cries Of Two-Month-Old Infants With Cleft Lip And Palate Predict Language Development published
Tue, 17 May 2011 00:00:00 PST
An infant child's cries are his or her way of communicating with the world. However, the baby's cries have more information to communicate beyond saying "I'm hungry," or "I'm tired." The complexity of melody and rhythm within a cry can be an early indicator of a child's pre-speech development...
Pre-Natal Diagnosis, Timely Treatment Key To Success For Growing Number Of Newborns With Clefts published
Fri, 22 Apr 2011 00:00:00 PST
Affecting more than 7,000 U.S. babies each year, cleft lip and/or cleft palate are the second most common birth defect, the cause of which continues to mystify scientists despite growing evidence of a complex interplay of genetic, environmental and lifestyle factors...
Technology Used To Assess How People View Faces With A Cleft Lip And Palate published
Fri, 15 Apr 2011 00:00:00 PST
The impact of physical attractiveness on social communication is a truth universally acknowledged. It is not surprising, therefore, that individuals with a cleft lip and palate have experienced social isolation and poor self-esteem. But how people really see faces affected by this anomaly has not been studied...
Corticosteroid Use During Pregnancy Not Linked To Facial Clefts In Infants published
Mon, 11 Apr 2011 09:00:00 PST
Corticosteroid use during pregnancy not linked to facial clefts in infants The use of corticosteroids during pregnancy does not appear to be associated with an increased risk of orofacial clefts in infants, according to an article in CMAJ (Canadian Medical Association Journal)...
Psychosocial Adjustment Of Adolescents With Cleft Lip And Palate published
Thu, 24 Mar 2011 00:00:00 PST
Adolescence is generally viewed as a socially and psychologically challenging period of development. For young people with cleft lip, cleft palate, or both, these challenges can be magnified. How their parents react can add another factor into these children's outlooks...
Migraine, Epilepsy Drug Topamax May Cause Newborn Cleft Palate published
Fri, 04 Mar 2011 10:00:00 PST
The FDA has warned that the drug prescribed for epilepsy named Topamax (topiramate) should not be used by women who are pregnant or plan on childbearing, due to a very high risk of offspring bearing cleft lip and palate defects occuring during the first trimester. Topiramate treats epilepsy in children and adults and was originally marketed as an anticonvulsant...
Dental Procedures For Cleft Lip And Palate Patients Bring Together Function And Looks published
Thu, 25 Nov 2010 02:00:00 PST
It may look the same, but it doesn't chew the same. Different dental treatment options for bilateral cleft lip and palate may result in similar aesthetic appearance, but they produce definite differences in jaw function. People with clefts of the lip and palate often have dental anomalies as well. The number, shape, and position of teeth can be affected...
Prenatal Knowledge Of Cleft Lip/Palate Shows Little Advantage Over Birth Discovery published
Thu, 25 Nov 2010 02:00:00 PST
Many expectant parents look forward to routine ultrasounds as their first opportunity to "see" their baby. But the ultrasound can reveal that the fetus has unexpected medical conditions, such as a diagnosis of cleft lip and palate. Despite the emotional distress the diagnosis can bring, it can also offer the opportunity to prepare for the child's future needs...
Prenatal Knowledge Of Cleft Lip/Palate Shows Little Advantage Over Birth Discovery published
Wed, 24 Nov 2010 04:00:00 PST
Many expectant parents look forward to routine ultrasounds as their first opportunity to "see" their baby. But the ultrasound can reveal that the fetus has unexpected medical conditions, such as a diagnosis of cleft lip and palate. Despite the emotional distress the diagnosis can bring, it can also offer the opportunity to prepare for the child's future needs...
2010 AAO-HNSF Miniseminars: Wednesday, Sept. 29, 2010 published
Thu, 30 Sep 2010 05:00:00 PST
The 2010 Annual Meeting & OTO EXPO of the American Academy of Otolaryngology - Head and Neck Surgery Foundation (AAO-HNSF), the largest meeting of ear, nose, and throat doctors in the world, convened September 26-29, 2010, in Boston, MA...
Researchers Find Mechanism Behind Cleft Palate Development published
Wed, 15 Sep 2010 04:00:00 PST
Researchers from Mount Sinai School of Medicine have found a new mechanism that explains why a certain gene mutation causes craniofrontonasal syndrome (CFNS), a disorder that causes cleft palate and other malformations in the face, brain, and skeleton. Cleft palate affects one of every 1,000 newborns. The research is published in the September 15 issue of Genes & Development...
Mental Retardation Research Published In Nature published
Thu, 05 Aug 2010 01:00:00 PST
Malfunction of a protein has been linked to a form of mental retardation that affects up to one out of every 500 males, says Nasser K. Yaghi, a Texas A&M University magna cum laude biology graduate who was selected to participate in a medical research project at Harvard that has been published in the journal Nature...
New Epigenetic Player In Mental Retardation And Facial Birth Defects published
Wed, 14 Jul 2010 00:00:00 PST
A subtle mutation affecting the epigenome - a set of dynamic factors that influence gene activity - may lead to an inherited form of mental retardation that affects boys, find researchers at Children's Hospital Boston. The disorder, which also involves cleft lip or cleft palate, appears to hinge on an enzyme working in a biological pathway that may offer several potential drug targets...
Research Sheds Light On Early Embryogenesis, Genetic Disease published
Sat, 15 May 2010 00:00:00 PST
Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births...
Novel Genes Associated With Risk For Oral Cleft Malformation Identified published
Tue, 04 May 2010 03:00:00 PST
An international consortium of scientists, led by researchers at Johns Hopkins University has identified two genes that when altered are closely associated with cleft lip and/or cleft palate. Cleft lip and cleft palate are among the world's most common congenital malformations and occur in one in every 700 births...
News From The Journal Of Clinical Investigation, April 26, 2010 published
Tue, 27 Apr 2010 04:00:00 PST
NEUROBIOLOGY: Too hot to handle: how heat causes pain Our body detects heat above 43 degrees Celsius as painful. The main detector of noxious heat is the protein TRPV1 on pain-sensing sensory nerve cells. Exactly how TRPV1 sensitivity to heat is regulated has not been clearly determined...
People With Facial Paralysis More Socially Adjusted Than Previously Thought published
Tue, 20 Apr 2010 01:00:00 PST
A smile means happiness, a frown sadness, a raised brow surprise. Even when languages and cultures differ, people have this universal form of communication. But Moebius syndrome, a rare congenital condition causing facial paralysis, can rob people of this basic connection, affecting social interaction...
Breakthrough For Babies Born With Severe Cleft Palates After Experiments At ISIS published
Fri, 19 Mar 2010 02:00:00 PST
Scientists working on a treatment for babies born with cleft palates have made a promising breakthrough and the first clinical trials are planned for early next year...
Team Approach Provides Better Care For Children With Cleft Lip And Palate published
Sat, 13 Mar 2010 01:00:00 PST
Children with a cleft lip or cleft palate are more likely to receive recommended age-appropriate health care when that care is provided by an interdisciplinary team rather than an individual provider. In a study encompassing three states, Arkansas, Iowa and New York, 24% of participants were not receiving team care...
Growth Factor Gene Shown To Be A Key To Cleft Palate published
Wed, 03 Feb 2010 03:00:00 PST
Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal...
Growth Factor Gene Shown To Be A Key To Cleft Palate published
Wed, 03 Feb 2010 02:00:00 PST
Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal...
Pitt Researcher To Co-Direct National Consortium On Facial Birth Defects published
Wed, 18 Nov 2009 00:00:00 PST
Researchers at the University of Pittsburgh and the University of Iowa will lead a $9 million, five-year initiative to study the cause of facial birth defects. The FaceBase Consortium will create an encyclopedic database of how the faces of children develop and what goes wrong to cause malformations...
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