Breaking news on cjd vcjd mad cow disease
Prion-Like Protein Plays A Key Role In Storing Long-Term Memories published
Tue, 31 Jan 2012 00:00:00 PST
Memories in our brains are maintained by connections between neurons called "synapses"...
Hidden Side Of Prion Diseases Discovered By Medical Researchers In Canada And The US published
Thu, 01 Dec 2011 02:00:00 PST
Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or "mad cow disease," have a hidden signature...
First Mouse Model To Study Important Aspect Of Alzheimer's published
Wed, 09 Nov 2011 00:00:00 PST
Hirano bodies are almost indescribably tiny objects found in nerve cells of people suffering from conditions such as Alzheimer's, mad cow and Lou Gehrig's diseases. Yet for decades, researchers weren't sure if these structures helped cause the conditions or appeared after onset of the disease and had some other role...
Cellular Stress Can Induce Yeast To Promote Prion Formation published
Mon, 25 Jul 2011 00:00:00 PST
It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in humans and animals. Prions trigger the misfolding and aggregation of their properly folded protein counterparts, but they usually need some kind of "seed" to get started...
Study Of Prion Diseases And Alzheimer's To Benefit From $600,000 Research Grants published
Sun, 24 Jul 2011 00:00:00 PST
The University of Western Ontario is one of nine universities which will share 2.9 million dollars in research grants announced by PrioNet Canada to study Prion diseases and neurodegenerative disorders including Alzheimer's...
Tracking Down BSE And Creutzfeldt-Jakob Disease published
Fri, 01 Jul 2011 00:00:00 PST
Prion diseases such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy (BSE) in cattle are transmissible neurodegenerative diseases linked to the aggregation of the prion protein in the central nervous system. It is known that the aggregation of prion proteins promotes neuronal decay with fatal consequences for the infected individual...
Rinderpest Is Dead; Second Disease In History Declared Eradicated published
Tue, 28 Jun 2011 10:00:00 PST
The Romans couldn't beat it when they ruled the world, but today in Rome the UN has declared the eradication of rinderpest, the second disease in all of human history to be successfully wiped out after smallpox. Scientists are celebrating victory over a deadly animal disease that cattle herders around the world have dreaded for millennia...
Drugs Being Developed To Tackle CJD Could Also Help Prevent Alzheimer's published
Thu, 09 Jun 2011 02:00:00 PST
Scientists funded by the Medical Research Council (MRC) and Science Foundation Ireland (SFI) have identified two antibodies which could help block the onset of Alzheimer's disease in the brain. The antibodies, ICSM-18 and ICSM-35, were already known to play a crucial role in preventing 'protein misfolding', the main cause of Creutzfeldt-Jakob disease (CJD), the human form of mad cow disease...
CDC Assesses Potential Human Exposure To Prion Diseases Study Results Reported In The Journal Of The American Dietetic Association published
Sun, 22 May 2011 21:00:00 PST
Researchers from the Centers for Disease Control and Prevention (CDC) have examined the potential for human exposure to prion diseases, looking at hunting, venison consumption, and travel to areas in which prion diseases have been reported in animals...
When Coroners Said No To Post-Mortem Tissue Collection They Were Wrong, Academics Argue published
Tue, 10 May 2011 03:00:00 PST
The Coroner's Society "failed" in its duty to protect public health by refusing to take part in vCJD study. The creation of a post-mortem tissue archive for a study of the human form of mad cow disease failed because of a "misguided" refusal by coroners to participate...
Fast, Sensitive Blood Test For Human Prion Disease published
Tue, 10 May 2011 02:00:00 PST
WHAT: Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), report that they have developed a method -10,000 times more sensitive than other methods - to detect variant Creutzfeldt-Jacob disease (vCJD) in blood plasma. vCJD is a type of prion disease in humans that leads to brain damage and death...
STERIS Pioneers Prion Decontamination Technologies published
Thu, 07 Apr 2011 05:00:00 PST
Following recent patient safety alerts, prion diseases - such as Creutzfeldt-Jakob disease (CJD) and variant CJD (vCJD) - are of increasing concern within the healthcare environment, as their causative agents can be extremely resistant to the cleaning, disinfection and sterilization methods currently used in many hospitals...
Canadian Blood Services To Expand Deferral Policy For vCJD published
Wed, 30 Mar 2011 01:00:00 PST
Canadian Blood Services is expanding its deferral policy for vCJD (variant Creutzfeldt -Jakob disease) policy to include Saudi Arabia. A new question will be added to the Record of Donation donor questionnaire asking each donor if he or she has spent a cumulative total of six months or more in Saudi Arabia between 1980 and 1996...
New Insights May Lead To Prevention, Treatments For Disorders That Involve Protein Misfolding published
Mon, 21 Mar 2011 02:00:00 PST
Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists at Brown University reports that cells can fix the problems themselves with only a little bit of help...
New Research Focuses On Prion Diseases published
Tue, 15 Mar 2011 03:00:00 PST
New research by Chongsuk Ryou, researcher at the UK Sanders-Brown Center on Aging and professor of microbiology, immunology and molecular genetics in the UK College of Medicine, may shed light on possible treatments for prion diseases...
Researchers Identify Biomarker For Creutzfeldt-Jakob Disease published
Thu, 10 Mar 2011 02:00:00 PST
Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease onset...
Potential Treatment For Prion Diseases published
Fri, 25 Feb 2011 01:00:00 PST
Scientists who examined more than 10,000 chemical compounds during the last year in search of potential new drugs for a group of untreatable brain diseases, are reporting that one substance shows unusual promise. The early positive signs for so-called prion diseases come from research in laboratory mice and cell cultures, they say in a report in ACS' Journal of Medicinal Chemistry...
Improving Understanding Of The Spread Of Infectious Prions published
Sat, 19 Feb 2011 00:00:00 PST
Researchers at the University of California, San Diego School of Medicine have identified the motors that move non-infectious prion proteins (PrPC) - found within many mammalian cells - up and down long, neuronal transport pathways...
World's First Blood Test For VCJD Developed In MRC Lab published
Fri, 04 Feb 2011 01:00:00 PST
The world's first accurate blood test for variant Creutzfeldt-Jakob disease (vCJD) has been developed by Medical Research Council (MRC) scientists. The prototype, which is 100,000 times more sensitive than any previous attempt, could transform the diagnosis and screening of the brain disease. Variant CJD, the human form of BSE (or mad cow disease) first emerged in 1995...
Researchers Create Prototype Test To Screen For Creutzfeldt-Jakob Disease (CJD) From Donor Blood published
Thu, 03 Feb 2011 10:00:00 PST
Evidence shows there is a risk of transmitting the neurodegenerative condition variant Creutzfeldt-Jakob disease (vCJD) through transfusion of blood and blood products, and thus also via surgery and dental procedures. Current strategies to reduce this risk in the UK are expensive and their benefit is uncertain...
News From The Journals Of The American Society For Microbiology published
Fri, 21 Jan 2011 01:00:00 PST
Nanoparticle Vaccine Protects Against Stomach Flu A new vaccine strategy using nanoparticles as carriers may be the key to developing a vaccine against norovirus, one of the most common causes of foodborne disease in the United States. Researchers from the Cincinnati Children's Hospital Medical Center report promising findings in the January 2011 isse of the Journal of Virology...
BSE Pathogens Can Be Transmitted By Air published
Mon, 17 Jan 2011 00:00:00 PST
Airborne prions are also infectious and can induce mad cow disease or Creutzfeldt-Jakob disorder. This is the surprising conclusion of researchers at the University of Zurich, the University Hospital Zurich and the University of Tübingen. They recommend precautionary measures for scientific labs, slaughterhouses and animal feed plants...
Prions That Cause Mad Cow Disease Can Spread Through Air published
Sat, 15 Jan 2011 10:00:00 PST
Prions, the agents that cause bovine spongiform encephalopathy (BSE or mad cow disease) and Creutzfeldt-Jakob disease, can spread through the air and induce infection, according to new research led by the University of Zurich; a discovery that may come as a great surprise to many, because until now it was thought airborne prions were harmless...
Researchers Identify Drug Target For Prion Diseases, Including "Mad Cow" published
Tue, 11 Jan 2011 01:00:00 PST
Scientists at the University of Kentucky have discovered that plasminogen, a protein used by the body to break up blood clots, speeds up the progress of prion diseases such as mad cow disease...
Discovery That Prions Mutate And Adapt To Host Environment Points To Normal Prion Protein As Most Effective Therapeutic Target For "Mad Cow" Disease published
Mon, 20 Dec 2010 01:00:00 PST
Scientists from the Florida campus of The Scripps Research Institute have shown that prions, bits of infectious protein that can cause fatal neurodegenerative disease such as bovine spongiform encephalopathy (BSE) or "mad cow disease," have the ability to adapt to survive in a new host environment...
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